CD40 Ligand (CD40L/CD154/TRAP) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. Recombinant Human CD40 Ligand is produced by E.coli expression system and the target gene encoding Met113-Leu261 is expressed.
Human β-Nerve Growth Factor (β-NGF) is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B...
Human β-Nerve Growth Factor (β-NGF) is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B...
IL-34 is a cytokine that promotes monocyte and macrophage differentiation and viability via colony-stimulating factor-1 receptor (CSF1R). The ED50 is 50-200 ng/mL as measured in a cell proliferation assay using M-NFS-60 mouse bone marrow cells.
Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 plays an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells and...
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 plays an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells and...
Mouse Interleukin 33 (IL-33) may regulates gene transcription in producer cells. IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.
Mouse Interleukin 33 (IL-33) may regulates gene transcription in producer cells. IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.
MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. A DNA sequence encoding the human MRAP (Tyr59-Ser172) was expressed with the Fc region of human IgG1 at the N-terminus.
HSP70 can serve a cytokine function to initiate both innate and adaptive immunity through activation of APC. HSP serves also a chaperone function and facilitates the presentation of antigen peptide to T cells.