Tissue-type plasminogen activator (TPA) is a protein that secreted into extracellular space. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, TPA plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and...
Tissue-type plasminogen activator (TPA) is a protein that secreted into extracellular space. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, TPA plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and...
Hepatocyte growth factor, also known as HGF, belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor, and acts as a multi-functional cytokine on cells of mainly...
Recombinant Human TNF RII belongs to the TNFR (tumor necrosis factor receptor) superfamily characterized by cysteine-rich extracellular domains. TNFRII is strongly expressed at the cartilage-pannus junction, and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA).
Recombinant Human TNF RII belongs to the TNFR (tumor necrosis factor receptor) superfamily characterized by cysteine-rich extracellular domains. TNFRII is strongly expressed at the cartilage-pannus junction, and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA).
SDF-1 also known as CXCL12 is belonging to the CXC chemokine family. SDF-1 binds primarily to CXC receptor 4 (CXCR4; CD184). The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription.
Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST has anti-anabolic effects on bone formation.
Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST has anti-anabolic effects on bone formation.
Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST has anti-anabolic effects on bone formation.
Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST has anti-anabolic effects on bone formation.
Claudin-6 (CLDN6) belongs to the claudins family. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function.
Interleukin 1 beta (IL-1β) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells.