FN-1501 is a potent inhibitor of Fms-like receptor tyrosine kinase 3 (FLT3) and cyclin-dependent kinase (CDK), and the IC50 for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3 with IC50s of 2.47, 0.85, 1.96 and 0.28 nM, respectively.
3-Hydroxypropionic acid sodium salt is a building block in the synthesis of a variety of compounds with industrial applications. 3-Hydroxypropionic acid sodium salt can be used to synthesize some degradable plastics and produce a series of C3 compounds.
Toluidine Blue O is a basic thiazine metachromatic dye with high affinity for acidic tissue components. Toluidine Blue has wide applications in vital staining in living tissues and a special stain.
OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain).
EC5026 (BPN-19186) is a first-in-class, potent and orally active soluble inhibitor of Epoxide Hydrolase (sEH). EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.
Tc-e 5003 is a selective inhibitor of PRMT1 with an IC50 of 1.5 µM against hPRMT1. Tc-e 5003 has anti-inflammatory properties in TLR4 signal transduction.
Lomitapide Mesylate is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.
ML-184 (CID2440433) is a selective GPR55 agonist with an EC50 of 250 nM and exhibits >100-fold selectivity for GPR55 over GPR35, CB1 and CB2. ML-184(CID2440433) increases proliferation of neural stem cells and promotes neuronal differentiation in vitro.
Ginsenoside Rk2 is a dammarane glycoside isolated from the processed ginseng (SG; Sun Ginseng), with anti-tumor, and anti-platelet aggregation activities.