Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
GANT58
GANT58 (NSC75503) is a potent GLI antagonist that inhibits GLI1-induced transcription with an IC50 of 5 μM.
Unesbulin
Unesbulin (PTC596) is a novel orally active and selective B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1) inhibitor, Unesbulin downregulating MCL-1 and inducing p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells.
Coptisine chloride
Coptisine chloride is an effective and non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM. Coptisine chloride is an effective H1N1 neuraminidase (NA-1) inhibitor with IC50 of 104.6 μg/mL, which can be used for influenza A virus (H1N1) infection.
Bergaptol
Bergaptol is a hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM.
Tyrphostin AG528
Tyrphostin AG528 (Tyrphostin B66) is an inhibitor of EGFR and ErbB2 with IC50 values of 4.9 and 2.1 μM, respectively.
MK-8245
MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.
GPR81 agonist 1
GPR81 agonist 1 is a potent and highly selective GPR81 agonist, with EC50 values of 58 nM and 50 nM for human and mouse GPR81, respectively.
CGP 60474
CGP60474 is a highly effective anti-endotoxin drug, It is an effective cyclin-dependent kinase (CDK) inhibitor (IC50 of CDK1/B, CDK2/E, CDK2/ A, CDK4/D, CDK5/ P25, CDK7/H and CDK9/T are 26, 3, 4, 216, 10, 200 and 13 nM, respectively). CGP60474 is a selective and ATP-competitive PKC inhibitor.
Sildenafil
Sildenafil is a Phosphodiesterase 5 Inhibitor with IC50 of 5.22 nM.
PSB-603
PSB 603 is a highly selective A 2B antagonist.
Cipepofol
Cipepofol (HSK3486), a psychomotor stabilizing agent, is a gamma-aminobutyric acid (GABA) receptor potentiator.
Osthenol
Osthenol (Ostenol) is a selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B.