Chemical Hay 28543 productos.

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  ML-SA5 

  ML-SA5 is a potent TRPML1 cation channel agonist that activates the entire endosomal TRPML1 (ML1) current in DMD myocytes with an EC50 of 285 nM and is more potent than ML-SA1. ML-SA5 has anticancer activity and can inhibit tumour growth.

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  ARP-100 

  ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1＇ pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM).

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  Fusidic acid

  Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome.

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  CDK12-IN-2 

  CDK12-IN-2 is a potent, selective and nanomolar CDK12 inhibitor (IC50=52 nM). CDK12-IN-2 is also a strong CDK13 inhibitor due to CDK13 is the closest homologue of CDK12. CDK12-IN-2 inhibits the phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II. CDK12-IN-2 can be used an excellent chemical probe for functional studies of CDK12.

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  CDK12-IN-2 

  CDK12-IN-2 is a potent, selective and nanomolar CDK12 inhibitor (IC50=52 nM). CDK12-IN-2 is also a strong CDK13 inhibitor due to CDK13 is the closest homologue of CDK12. CDK12-IN-2 inhibits the phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II. CDK12-IN-2 can be used an excellent chemical probe for functional studies of CDK12.

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  Myrcene

  Myrcene is a monoterpene compound found in many plants that inhibits both MAP kinase and NF-κB pathways, thereby suppressing colonic inflammation.

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  dl-Carvone

  dl-Carvone is a monoterpene ketone found in the essential oils of medicinal plants, and is also a plant antifungal, as well as an insecticide with anti-inflammatory activity.

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  Lotilaner

  Lotilaner is a first-in-class, highly selective inhibitor of gamma-aminobutyric acid (GABA) gated chloride channels (GABACls) against mites. It has antiparasitic activity with an IC50 value of 23.84 nM against the Drosophila GABA receptor and can be used in studies related to helminth mite blepharitis.

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  AOH1160

  AOH1160 is a potent, first-in-class, orally active inhibitor of proliferating cell nuclear antigen (PCNA) that also interferes with DNA replication, blocks homologous recombination-mediated DNA repair, as well as causes cell cycle arrest and induces apoptosis, and can be used in oncology-related studies.

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  Lotilaner

  Lotilaner is a first-in-class, highly selective inhibitor of gamma-aminobutyric acid (GABA) gated chloride channels (GABACls) against mites. It has antiparasitic activity with an IC50 value of 23.84 nM against the Drosophila GABA receptor and can be used in studies related to helminth mite blepharitis.

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  Lotilaner

  Lotilaner is a first-in-class, highly selective inhibitor of gamma-aminobutyric acid (GABA) gated chloride channels (GABACls) against mites. It has antiparasitic activity with an IC50 value of 23.84 nM against the Drosophila GABA receptor and can be used in studies related to helminth mite blepharitis.

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  Añadir a Mis productos destacados
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  Polyethylenimine (MW 300)

  Polyethylenimine is a surfactant that acts as a polyelectrolyte multilayer on a charged surface, providing that surface with a biocompatible coat.

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