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Iclepertin (BI 425809) is an oral glycine transporter-1 (GlyT1) inhibitor being developed for the study of cognitive impairment associated with schizophrenia (CIAS).
E7386 is an orally active and selective inhibitor of β-catenin/CBP protein interactions and is a key node in the long-studied Wnt/β-catenin cancer pathway.
(E/Z)-Polydatin (E/Z)-Piceid) is a single-crystal compound originally isolated from the roots and rhizomes of Echinacea purpurea with antiplatelet aggregation, anti-low density lipoprotein (LDL) oxidation, cardioprotective, anti-inflammatory and immunomodulatory properties.
DSPE-PEG-Biotin (MW 2000) is a PROTAC linker, which belongs to the PEG class. It can be used to synthesize PROTAC molecules.
Cytidine-5'-monophospho-N-acetylneuraminic acid is a nucleotide.
MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2.
CCT251545 is an orally active, potent WNT inhibitor with an IC50 value of 5 nM for WNT inhibition in 7dF3 cells.In addition, CCT251545 is a selective chemical probe for studies related to the roles of CDK8 and CDK19 in human diseases.
CCT251545 is an orally active, potent WNT inhibitor with an IC50 value of 5 nM for WNT inhibition in 7dF3 cells.In addition, CCT251545 is a selective chemical probe for studies related to the roles of CDK8 and CDK19 in human diseases.
Prostaglandin A2 (PGA2) is a endogenous metabolite derived from arachidonic acid, it plays a vital role in the induction of apoptosis. Prostaglandin A2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. Prostaglandin A2 induces p53-dependent apoptosis.
Prostaglandin A2 (PGA2) is a endogenous metabolite derived from arachidonic acid, it plays a vital role in the induction of apoptosis. Prostaglandin A2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. Prostaglandin A2 induces p53-dependent apoptosis.
SN52 is a novel potent, competitive, and cell-permeable inhibitor of nuclear factor-kappaB (NF-κB). SN52 is a variant of the SN50 peptide and inhibits the nuclear translocation of p52-RelB heterodimers. SN52 has a strong radiosensitization effect on prostate cancer cells.