Polyethylenimine is a surfactant that acts as a polyelectrolyte multilayer on a charged surface, providing that surface with a biocompatible coat.
Almonertinib mesylate is an orally active, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR sensitization and T790M resistance mutations, and also shows strong inhibitory activity against T790M, T790M/L858R, and T790M/Del19, with IC50 of 0.37, 0.29, and 0.21 nM, respectively. The IC50 of T790M/Del19 was 0.37,...
Almonertinib mesylate is an orally active, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR sensitization and T790M resistance mutations, and also shows strong inhibitory activity against T790M, T790M/L858R, and T790M/Del19, with IC50 of 0.37, 0.29, and 0.21 nM, respectively. The IC50 of T790M/Del19 was 0.37,...
5-FAM Maleimide is a derivative of 5-FAM in which the Maleimide group is able to react with protein molecules containing thiols to form stable thioether bonds that can be used to label proteins.
Ferroptocide is a small molecule inhibitor of thioredoxin, as well as an inducer of ferroptosis, with antitumor activity.
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE is a phospholipid that can be used in studies related to drug delivery.
1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine is the major degradation product of deltamethrin metabolized by the prokaryotic protein (CYP6A14 and CYP6N6) complex in vitro.
KYL peptide is an antagonistic peptide that selectively targets EphA4, and its binding to the ligand-binding domain of EphA4 effectively alleviates Aβ-induced synaptic dysfunction and synaptic plasticity defects in AD mice. In addition, KYL peptide can promote nerve regeneration after injury and modulate immune response.
KYL peptide is an antagonistic peptide that selectively targets EphA4, and its binding to the ligand-binding domain of EphA4 effectively alleviates Aβ-induced synaptic dysfunction and synaptic plasticity defects in AD mice. In addition, KYL peptide can promote nerve regeneration after injury and modulate immune response.
ARV-393 is an orally active PROTAC degrader targeting BCL6 for studies related to diffuse large B-cell lymphoma. ARV-393 utilizes the ubiquitin-proteasome system to target the degradation of BCL6.
ARV-393 is an orally active PROTAC degrader targeting BCL6 for studies related to diffuse large B-cell lymphoma. ARV-393 utilizes the ubiquitin-proteasome system to target the degradation of BCL6.
Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis.