Maribavir is an effective inhibition of wild-type pUL97-catalyzed histone phosphorylation,IC50 3 nM. Maribavir acts effectively against HCMV and Epstein-Barr virus (EBV).
Cedirogant (ABBV-157) is an orally active RORγt reverse agonist that can be used in the study of psoriasis.
Rivastigmine (S-Rivastigmine) is an orally active, potent cholinesterase (ChE) inhibitor that inhibits butyrylcholinesterase (BChE) and acetylcholinesterase (AChE),IC50 0.037 μM and 4.15 μM, respectively. Rivastigmine can pass through the blood-brain barrier (BBB). Rivastigmine is an parasympathetic or cholinergic agent used to study dementia caused by...
Cedirogant (ABBV-157) is an orally active RORγt reverse agonist that can be used in the study of psoriasis.
Cedirogant (ABBV-157) is an orally active RORγt reverse agonist that can be used in the study of psoriasis.
Cddo-2p-im is a CDDO imidazolid analogue with chemoprophylaxis. Cddo-2p-im reduced the size and severity of lung tumors in mouse lung cancer models. Cddo-2p-im is an orally active necroptosis inhibitor that can be used in ischemia/reperfusion (I/R) studies.
Cddo-2p-im is a CDDO imidazolid analogue with chemoprophylaxis. Cddo-2p-im reduced the size and severity of lung tumors in mouse lung cancer models. Cddo-2p-im is an orally active necroptosis inhibitor that can be used in ischemia/reperfusion (I/R) studies.
Coenzyme Q10 (CoQ10) forms the electron transport chain and participates in cellular aerobic respiration.
AF40431 is the first reported small molecule ligand of sortilin with IC50 of 4.4 µM and Kd of 0.7 µM. AF40431 binds to the neurotensin binding site of sortilin.
Hyodeoxycholic acid is a secondary bile acid formed by intestinal flora in the small intestine and is an agonist of TGR5 (GPCR19). In CHO cells, the EC50 value is 31.6 µM.