MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity.
Licorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a saponin derived from licorice.
WNK463 is an oral WNK kinase inhibitor for WNK1, WNK2, WNK3, and WNK4 IC50 The values are 5 nM, 1 nM, 6 nM, and 9 nM, respectively.
Neutral Red is a nitrogenous pH indicator with its pKi The value is 6.8, which is an indicator of acidification inside the thylakoid body. Neutral Red stains lysosomals red.
Tricosadiynoic acid, 10,12-Tricosadiynoic acid, is A highly specific, selective, high-affinity acyl-coa oxidase-1 (ACOX1) inhibitor with oral activity. Tricosadiynoic acid can improve mitochondrial lipid and ROS metabolism and can be used to study metabolic diseases caused by high fat diet or obesity.
Tricosadiynoic acid, 10,12-Tricosadiynoic acid, is A highly specific, selective, high-affinity acyl-coa oxidase-1 (ACOX1) inhibitor with oral activity. Tricosadiynoic acid can improve mitochondrial lipid and ROS metabolism and can be used to study metabolic diseases caused by high fat diet or obesity.
NPX800 is an oral HSF1 inhibitor of FIC. NPX800 has the potential to be used in cancer research.
ABBV-CLS-484 (Osunprotafib) is an first-in-class, orally active, potent PTPN2/PTPN1 active site inhibitor with an EC50 of 0.176 μM that enhances the sensitivity of tumor cells to IFNγ and promotes T cell activation and function.
Dichlorophen (DDM) is a tapeworm repellent compound. Dichlorophen is an antimicrobial agent that is active against tapeworms, protozoa, fungi and bacteria.
Enoxolone (Glycyrrhetin) is a β -aromatic resin alcohol pentacyclic triterpenoid derivative obtained by Glycyrrhetin hydrolysis, with anti-ulcer, anti-inflammatory and anti-proliferation properties.
CD38 inhibitor 1 (COMPOUND 78c, CD38-in-78C) was an effective INHIBITOR of CD38, with IC50 of 7.3 nM and 1.9 nM for human AND mouse CD38 respectively.