Calcitonin salmon is a calcium-regulating hormone that is a dual agonist of amylin and calcitonin receptors that stimulate bone production and inhibit bone resorption.
Ralaniten (EPI-002) is an effective and orally active androgen receptor N-terminal domain (AR-NTD) antagonist. Ralaniten inhibits AR transcriptional activity,IC50 The value is 7.4 μM. Ralanites can be used in the study of castration-resistant prostate cancer (CRPC).
Ralaniten (EPI-002) is an effective and orally active androgen receptor N-terminal domain (AR-NTD) antagonist. Ralaniten inhibits AR transcriptional activity,IC50 The value is 7.4 μM. Ralanites can be used in the study of castration-resistant prostate cancer (CRPC).
TPX-0046 is a novel RET/SRC inhibitor that is used against RET in Ba/F3 cell proliferation assaysG810R The average IC50 is 17 nM.
Ralaniten (EPI-002) is an effective and orally active androgen receptor N-terminal domain (AR-NTD) antagonist. Ralaniten inhibits AR transcriptional activity,IC50 The value is 7.4 μM. Ralanites can be used in the study of castration-resistant prostate cancer (CRPC).
RCGD423 is a gp130 regulator that prevents joint cartilage degeneration and promotes its repair.
S-(4-Hydroxybenzyl)glutathione is a glutathione derivative. S-(4-Hydroxybenzyl)glutathione inhibits in vitro binding of erythoxylate to cerebral glutamate receptors,IC50 The value is 2 μM.
Methyl α-D-glucopyranoside can be used in a study to investigate saccharide-mediated protection of chaotropic-induced deactivation of concanavalin A.
Phenyl-p-benzoquinone (PBQ; 2-Phenyl-1,4-benzoquinone) stimulus trigger a different peripheral cytokine cascade compared to acetic acid, it induces writhing response dependent on IL-18, IFNγ and endothelin-1.
UC2288 is a novel p21 attenuator with cellular permeability and oral activity (relatively selective activity for P21), based on the structural synthesis of sorafenib. UC2288 down-regulated the expression of P21 mRNA and reduced the level of P21 protein independently of p53, and had little effect on the stability of P21 protein. UC2288 did not inhibit...
FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation.
Autotaxin Modulator 1 is an Autotaxin (ATX) inhibitor of Autotaxin (ATX). Autotaxin Modulator 1 is expected to be used for demyelination caused by injury or disease, as well as for the study of proliferative diseases such as tumors.