STAT5-IN-2 is an inhibitor of STAT5 in K562 and KU812 cells EC50 9 μM and 5 μM respectively, the name in Document 1 is 17f. STAT5-IN-2 has highly effective antileukemia activity.
RCGD423 is a gp130 regulator that prevents joint cartilage degeneration and promotes its repair.
RCGD423 is a gp130 regulator that prevents joint cartilage degeneration and promotes its repair.
Trans-Aconitic acid is present in normal human urine and may be abundantly present in Reye syndrome and organic aciduria. trans-Aconitic acid is a substrate of trans-pyruvate 2-methyltransferase.
diABZI (STING agonist-1) trihydrochloride is a selective agonist of interferon gene-stimulated receptor (STING), with EC50 scores of 130 nM and 186 nM in mice and humans, respectively.
diABZI (STING agonist-1) trihydrochloride is a selective agonist of interferon gene-stimulated receptor (STING), with EC50 scores of 130 nM and 186 nM in mice and humans, respectively.
Evixapodlin (PD-1/ PD-L1-in 7) is an inhibitor of human PD-1/PD-L1 protein/protein interaction with an IC50 of 0.213 nM. Evixapodlin has anti-cancer and anti-virus properties.
Autotaxin Modulator 1 is an Autotaxin (ATX) inhibitor of Autotaxin (ATX). Autotaxin Modulator 1 is expected to be used for demyelination caused by injury or disease, as well as for the study of proliferative diseases such as tumors.
Pristane (Norphytane) is a naturally saturated terpene alkane found in small amounts in many plants, various Marine organisms, and is the most active component in mineral oils. Pristane is a non-antigenic adjuvant that induces MHC Class II restrictive arthritis T cells in rats.
WS3 is a β cell proliferation inducer, which can promote the β cell proliferation of primary rat and human islets. WS3 can be used in the study of type I diabetes.
Relacorilant is a selective, oral bioeffective glucocorticoid receptor antagonist (Ki of 7.2 nM in HepG2 TAT assay and 12,81.2 nM in rat, human and monkey glucocorticoid receptor in cell-based assay). Relacorilant can be used in studies of Cushing's syndrome.