NLRP3-IN-10 is a potent NLRP3 inhibitor with an IC50 of 251.1 nM for inhibition of IL-1β. NLRP3-IN-10 attenuates the formation of ASC speckles and inhibits the activation of NLRP3 inflammatory vesicles.
NLRP3-IN-10 is a potent NLRP3 inhibitor with an IC50 of 251.1 nM for inhibition of IL-1β. NLRP3-IN-10 attenuates the formation of ASC speckles and inhibits the activation of NLRP3 inflammatory vesicles.
NLRP3-IN-11 is a NLRP3 protein inhibitor that is biologically active with an IC50 value of
NLRP3-IN-10 is a potent NLRP3 inhibitor with an IC50 of 251.1 nM for inhibition of IL-1β. NLRP3-IN-10 attenuates the formation of ASC speckles and inhibits the activation of NLRP3 inflammatory vesicles.
MAP4K4-IN-3 is a potent and selective MAP4K4 inhibitor with an IC50 of 14.9 nM in kinase assay, and an IC50 of 470 nM in cell assay.
MAP4K4-IN-3 is a potent and selective MAP4K4 inhibitor with an IC50 of 14.9 nM in kinase assay, and an IC50 of 470 nM in cell assay.
2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2).
Isoluminol (4-Aminophthalhydrazide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
TEI-9647 is a Vitamin D3 Lactone analogue, and it is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 blocks both 1α,25(OH)2D3-mediated HL-60 cell differentiation and also activation of the luciferase reporter in COS-7 cells that has been transfected with the cDNA containing the DRE of the rat 25(OH)D3-24-hydroxylase gene and cDNA of...