Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
(R)-ZINC-3573
(R)-ZINC-3573 is a selective Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist with an EC50 value of 740 nM. (R)-ZINC-3573 can be used as a MRGPRX2 probe for the research of pain and itch.
(R)-ZINC-3573
(R)-ZINC-3573 is a selective Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist with an EC50 value of 740 nM. (R)-ZINC-3573 can be used as a MRGPRX2 probe for the research of pain and itch.
BT2
BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC). BT2 is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM.
BT2
BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC). BT2 is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM.
Reproxalap
Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal.
Neratinib maleate
Neratinib (HKI-272) maleate is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively.
Reproxalap
Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal.
Reproxalap
Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal.
PreScission Protease
PreScission Protease is a recombinantly expressed 3C protease of human rhinovirus type 14 with a GST tag in Escherichia coli that specifically recognizes the octapeptide sequence Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro or the core pentapeptide sequence Leu-Phe-Gln-Gly-Pro at low temperature (4°C) and cleaves between Gln and Gly amino acid residues. Pro and...
PreScission Protease
PreScission Protease is a recombinantly expressed 3C protease of human rhinovirus type 14 with a GST tag in Escherichia coli that specifically recognizes the octapeptide sequence Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro or the core pentapeptide sequence Leu-Phe-Gln-Gly-Pro at low temperature (4°C) and cleaves between Gln and Gly amino acid residues. Pro and...
