Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. PCNA also participates in the processing of branched intermediates that arise during the lagging strand DNA synthesis.
Cadherin-16 (CDH16) is a single-pass type I membrane protein which contains six cadherin domains. CDH16 is exclusively expressed in kidney, where the protein functions as the principal mediator of homotypic cellular recognition. It plays a role in the morphogenic direction of tissue development.
Human IFN-α2a and -α2b (HEK293) are allelic variants of the same gene, the IFN-α subtype is classified as an intermediate/strong ISG inducer and has strong antiviral activity against influenza A virus.
Lacutamab (IPH4102) is a humanized monoclonal antibody (mAb) directed against the immune receptor molecule KIR3DL2, produced by recombinant technology in CHO cells. Lacutamab can be used in research of cutaneous T-cell lymphoma.
Recombinant mouse fibroblast growth factor 4 was produced by escherichia coli expression system and expressed the target gene encoding Ser67 -- Leu202. Accession # : P11403.
Recombinant Human KGF/FGF-7 Protein (HEK293) is a mitogenic factor specific to epithelial cells and keratinocytes, it plays an important role in the development of kidney and lung, as well as angiogenesis and wound healing.
Insulin-like growth factor I (IGF1) binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is 20-100 ng/ml.
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type domain, which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states.
Prostaglandin-D2 Synthase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia,...
Recombinant human Apolipoprotein H(APOH) protein (HEK293, His) was expressed in HEK293 cells with a His tag on the N-terminal. Apolipoprotein H is the primary target of antiphospholipid antibodies (aPLs) found in many patients with systemic lupus erythematosus and antiphospholipid syndrome (APS).
The recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression systems, and the target gene encoding Asp23-Asp126 is expressed by 6His tag at the C-terminal. Protein number: P07766.
Human CXCL4/PF-4 is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4/PF-4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair.