Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases.
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. Protein G was found to be a powerful reagent for the detection of IgG, and consequently the antigen against which these antibodies are directed. It was used in Western blot analyses to detect various antigen-antibody complexes on...
Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
Recombinant Human BAFF Protein is a member of the tumor necrosis factor (TNF) family and is expressed in T cells, macrophages, monocytes and dendritic cells, stimulating the functions of B cells and T cells, and is an important factor for the survival and maturation of peripheral B cells.
Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP-1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens. The target gene encoding Phe20-Asn469 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA...
FABP4 is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family.
Siglec-6, also known as CD327, mediates sialic-acid dependent binding to cells. Siglec-6 binds to alpha-2,6-linked sialic acid.
Recombinant human Hepatocyte Growth Factor (rhHGF) , also known as hepatopoietin-A and scatter factor, is a pleiotropic mitogen belonging to the peptidase S1 family (plasminogen subfamily). It is produced by mesenchymal cells and acts on epithelial cells, endothelial cells and haemopoietic progenitor cells.
Recombinant human transforming growth factor β 1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The ED50 for this effect is 4-40 pg/ml.
Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash.
Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into...
Recombinant Human EGF Protein (HEK293) is an important class of growth factors.