Dickkopf-related protein 1(DKK-1) secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.
Recombinant human β-1, 4-galactosyl transferase 1 is produced by the mammalian expression system, and the target gene encodes Gly44-Ser398(Tyr285Leu) expressing the 6His tag at the C-terminus. Protein number: P15291.
R-spondin-1/RSPO1 is a secreted protein that can activate Wnt signaling and contains 2 FU (furin-like) repeats and 1 TSP type-1 domain, belonging to the R-spondin family. Protein number: Q2MKA7-1 (R31-A263).
Recombinant Human Vitronectin Protein is a secreted glycoprotein synthesized in the liver. It mainly circulates in the form of monomers, but can undergo conformational changes to form disulfide bond-connected multimers.
Oncostatin M (OSM) is a multifunctional cytokine, and belongs to Interleukin-6 (IL-6) subfamily, including IL-11, leukemia inhibitory factor (LIF), ciliary neurotropic factor, cardiotrophin-1, and novel neurotropin-1. ED50 < 10.0 ng/ml, measured by a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 1.0 × 105 units/mg.
Interleukin 12 (IL-12) has important immunological functions. IL12 facilitates hematopoietic stem cell proliferation, induces NK cell proliferation, and potentiates the expansion and late activation of Th1 CD4+ T cells.
Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into...
Recombinant human Endostatin protein (P. pastoris) is determined by the formation of endothelial cells. Endostatin concentration of 10 μg/ mL showed obvious anti-angiogenesis effect. Protein structure: Endostatin (ALA1571-Lys1754), Accession # P39060.
Recombinant mouse Sonic Hedgehog gene was prepared by escherichia coli expression system and the target gene encoding Cys25-Gly198 was expressed. Accession # : Q62226.
Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml,...
Interleukin-1 Beta (IL-1β) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. ED50 < 10.0 pg/ml, measured by the dose-dependent stimulation of mouse D10.G4.1 helper T cells, corresponding to a specific activity of 1.0 × 108 IU/mg.
Recombinant Human TGF-β2 Protein is a multifunctional cytokine that regulates cell proliferation, growth, differentiation and movement, as well as the synthesis and deposition of extracellular matrix.