Antibody
Antibody Hay 61873 productos.
Recombinant Human IGF-I (E.coli, 67AA)
Insulin-like growth factor I (IGF1) binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is 20-100 ng/ml.
Omalizumab
Omalizumab is a recombinant DNA-derived humanized IgG1k monoclonal antibody that specifically binds to free human immunoglobulin E (IgE) and to membrane-bound form of IgE (mIgE).
Domvanalimab
Domvanalimab (AB154) is an anti-TIGIT humanized monoclonal antibody. Domvanalimab binds human TIGIT9 and blocks the TIGIT-CD155 interaction. Domvanalimab can be used in research of cancer.
Spesolimab
Spesolimab (BI 655130) is an anti-IL-36R antibody. IL-36 involves in immune system, as Spesolimab can be used for palmoplantar pustulosis (PPP) research. Spesolimab is associated with the reduction of biomarkers linked to innate, Th1/Th17, and neutrophilic pathways.
Recombinant Human HGFR Protein (Mammalian, C-Fc)
Recombinant Human HGFR Protein is a glycosylation receptor tyrosine kinase, which plays a central role in epithelial morphogenesis and cancer development.
Recombinant Human IL-6R (CHO)
Interleukin-6 Receptor Alpha belongs to the type I cytokine receptor family. It binds specifically to IL-6 and depends on gp130 to transmit signals. Measured in a cell proliferation assay using M1 cells in the presence of 10.0 ng/ mL human IL-6, the ED50 is < 0.2 μg/mL.
Recombinant Human Oncostatin M Protein (HEK293)
Oncostatin M (HEK293) is also known as OSM, is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth.
Dostarlimab
Dostarlimab (TSR-042) is a humanized anti-PD-1 monoclonal antibody. Dostarlimab binds with high affinity to human PD-1 and competitively inhibits its interaction with its ligands, PD-L1 and PD-L2, with IC50s of 1.8 and 1.5 nM, respectively.
Recombinant Human PDGF-BB Protein (HEK293, C-His)
Recombinant Human PDGF-BB Protein (HEK293)
Recombinant Human IFNγ (CHO)
Human Interferon gamma (hIFN-γ) (CHO) is a dimerized soluble cytokine that is the only member of the type II class of interferons.
Ontamalimab
Ontamalimab (SHP647) human IgG2 anti-MAdCAM-1 monoclonal antibody specifically blocks the binding of α4β7 integrins to human mucosal addressin adhesion molecule-1 (MAdCAM1) ligand, thereby decreasing the migration of lymphocytes into the intestine. Ontamalimab may be used in studies related to ulcerative colitis (UC).
Recombinant Human Desmoplakin/DSP Protein (E. coli, N-His)
DSP proteins are major components of desmosomes and are critical for the structural integrity of various tissues. In cardiomyocytes, DSP regulates profibrotic gene expression through MAPK14/p38 MAPK activation and increased TGFB1 protein.