Recombinant Human RANK (C-6His) is produced by Mammalian expression system and the target gene encoding Ile30-Pro212 is expressed with a 6His tag at the C-terminus.
Recombinant Human IL-36RA Protein (originally named IL-1F5) can antagonize IL-36α, β or γ-induced NF-RrpB signaling by binding to IL-1Rrp2 receptor, thereby preventing the initiation of functional signals.
Recombinant Mouse Interleukin-17F is produced by Mammalian expression system and the target gene encoding Arg29-Ala161 is expressed with a 6His tag at the C-terminus. Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
Recombinant Human IL-36RA Protein (originally named IL-1F5) can antagonize IL-36α, β or γ-induced NF-RrpB signaling by binding to IL-1Rrp2 receptor, thereby preventing the initiation of functional signals.
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. ED50 < 5.0 pg/ml, measured in a cell proliferation assay using FDC-P1 cells, corresponding...
Recombinant Human Interleukin-31 (IL-31) signals through IL-31 receptor A and oncostatin M receptor subunits and can activate STAT3 through receptors and maybe involve in skin immunity.
Recombinant Human IL-22 Protein (Interleukin-22) is produced by T lymphocytes, inhibits Th2 cells from producing IL-4, and induces acute reactants in the liver and pancreas.
IkB alpha (NFKBIA, IKBA) is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NFKBIA inhibits NF-kB by masking the nuclear localization signals (NLS) of NF-kB proteins and keeping them sequestered in an inactive state in the cytoplasm. NFKBIA blocks the ability of NF-κB transcription factors to bind to...
The recombinant s. pyogenes serotype M1 cas9 consists of 1407 amino acids and predicts a molecular mass of 163 kDa.
Recombinant human transferrin is produced by mammalian expression system, and the target gene is encoded as Val20-Pro698, which is expressed by 6His marker at the C-terminal. Protein number: AAA61140.1.
Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.
Recombinant Mouse RANK (Receptor Activator of NF-kappa B) is produced by Mammalian expression system and the target gene encoding Val31-Ser214 is expressed with a 6His tag at the C-terminus. RANK can activate signaling pathways such as NF-κB, JNK, ERK, p38, and Akt/PKB, through TRAF protein phosphorylation after binding its ligand RANKL.