ZM 336372 is a potent, selective ATP-competitive inhibitor of c-Raf in vitro (IC50 = 70 nM for inhibition of human c-Raf).
ZM 336372 is a potent, selective ATP-competitive inhibitor of c-Raf in vitro (IC50 = 70 nM for inhibition of human c-Raf).
ZM 39923 is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
ZM 39923 is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
ZM-241385 is a high affinity antagonist ligand selective for the adenosine A2A receptor.
ZM-241385 is a high affinity antagonist ligand selective for the adenosine A2A receptor.
ZM-241385 is a high affinity antagonist ligand selective for the adenosine A2A receptor.
ZM323881 is a potent and selective VEGFR2 inhibitor with IC50 of 2 nM and almost has no activity on VEGFR1, PDGFRβ, FGFR1, EGFR and ErbB2.
ZM323881 is a potent and selective VEGFR2 inhibitor with IC50 of 2 nM and almost has no activity on VEGFR1, PDGFRβ, FGFR1, EGFR and ErbB2.
ZM447439 is the first Aurora family kinase inhibitor with IC50 of 50 nM for Aurora B kinase.
ZM447439 is the first Aurora family kinase inhibitor with IC50 of 50 nM for Aurora B kinase.
ZM447439 is the first Aurora family kinase inhibitor with IC50 of 50 nM for Aurora B kinase.