Zuranolone also known as SAGE-217, is a potent GABAA receptor agonist with EC50 values of 296 nM and 163 nM for α1β2γ2 and α4β3δ GABAA receptors.
Zuranolone also known as SAGE-217, is a potent GABAA receptor agonist with EC50 values of 296 nM and 163 nM for α1β2γ2 and α4β3δ GABAA receptors.
Zuranolone also known as SAGE-217, is a potent GABAA receptor agonist with EC50 values of 296 nM and 163 nM for α1β2γ2 and α4β3δ GABAA receptors.
Zuranolone also known as SAGE-217, is a potent GABAA receptor agonist with EC50 values of 296 nM and 163 nM for α1β2γ2 and α4β3δ GABAA receptors.
Zymosan A can increase the level of cyclin D2, suggesting the role of cyclin D2 in macrophage activation and proliferation. After injection of galactosamine, it aggravated acute liver injury, suggesting that some non-parenchymal cells besides Kupfer's cells were involved in fermentase action.
Zymosan A can increase the level of cyclin D2, suggesting the role of cyclin D2 in macrophage activation and proliferation. After injection of galactosamine, it aggravated acute liver injury, suggesting that some non-parenchymal cells besides Kupfer's cells were involved in fermentase action.
ZZW-115 is a potent NUPR1 inhibitor with a Kd of 2.1 μM and an IC50 of 0.42 μM in Hep2G cells and 7.75 μM in SaOS-2 cells. zZW-115 showed significant antitumor activity through interaction with NUPR1.
ZZW-115 is a potent NUPR1 inhibitor with a Kd of 2.1 μM and an IC50 of 0.42 μM in Hep2G cells and 7.75 μM in SaOS-2 cells. zZW-115 showed significant antitumor activity through interaction with NUPR1.
ZZW-115 is a potent NUPR1 inhibitor with a Kd of 2.1 μM and an IC50 of 0.42 μM in Hep2G cells and 7.75 μM in SaOS-2 cells. zZW-115 showed significant antitumor activity through interaction with NUPR1.
[Ala11,D-Leu15]-Orexin B (human) acetate is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B (human) acetate shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (EC50=52 nM).
[Ala11,D-Leu15]-Orexin B (human) acetate is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B (human) acetate shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (EC50=52 nM).
[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.