Recombinant Human TNF-α (E. coli)

Recombinant human TNF-α protein (E. coli) is a homotrimer with a subunit molecular mass of 17.3 kDa. TNF-a plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. ED50 < 30.0 pg/ml, measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D, corresponding to a specific activity of > 3.3 × 10⁷ units/mg.