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XAV-939
S-S1180-10mg
Producto nuevo
XAV-939
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Ficha de datos
| Size | 10mg |
| Target | Moleculas Pequeñas |
| CAS Number | 284028-89-3 |
| Small Target | Wnt/beta-catenin |
| Pathway | Stem Cells & Wnt |
| Smiles | OC1=C2CSCCC2=NC(=N1)C3=CC=C(C=C3)C(F)(F)F |
Más información
XAV-939 (NVP-XAV939) selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2inhibition with IC50of 11 nM/4 nM in cell-free assays, regulates axin levels and does not affect CRE, NF-κB or TGF-β.