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Shikonin
S-S8279-20mg
Producto nuevo
Shikonin
Al comprar este producto puede obtener hasta 15 puntos de fidelidad. Su cesta totalizará 15 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 3.00EUR.
Ficha de datos
| Size | 20mg |
| Target | Moleculas Pequeñas |
| CAS Number | 54952-43-1 |
| Small Target | Anti-infection |
| Pathway | Microbiology |
| Smiles | CC(C)=CCC(O)C1=CC(=O)C2=C(O)C=CC(=C2C1=O)O |
Más información
Shikonin, a potent and specific Pyruvate kinase M2 (PKM2)inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channelactivity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-α (TNF-α)and prevents activation of nuclear factor-κB (NF-κB)pathway via proteasomeinhibition.