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Adavivint (SM04690)
S-S8761-25mg
Producto nuevo
Adavivint (SM04690)
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Ficha de datos
| Size | 25mg |
| Target | Moleculas Pequeñas |
| CAS Number | 1467093-03-3 |
| Small Target | Wnt/beta-catenin |
| Pathway | Stem Cells & Wnt |
| Smiles | CC(C)CC(=O)NC1=CN=CC(=C1)C2=CC3=C([NH]N=C3C4=NC5=C([NH]4)C(=CN=C5)C6=CC=CC(=C6)F)C=C2 |
Más información
Adavivint (SM04690,Lorecivivint) is a potent and specific inhibitor of canonical Wnt signalingwith an EC50 of 19.5 nM for inhibiting the TCF/LEF reporter. It is ∼150- to 500-fold more potent than the other known Wnt inhibitors across multiple cellular assays.