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V-9302
S-S8818-100mg
Producto nuevo
V-9302
Al comprar este producto puede obtener hasta 104 puntos de fidelidad. Su cesta totalizará 104 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 20.80EUR.
Ficha de datos
| Size | 100mg |
| Target | Moleculas Pequeñas |
| CAS Number | 1855871-76-9 |
| Small Target | Amino acid transport |
| Pathway | Transmembrane Transporters |
| Smiles | CC1=CC(=CC=C1)COC2=C(CN(CCC(N)C(O)=O)CC3=CC=CC=C3OCC4=CC=CC(=C4)C)C=CC=C2 |
Más información
V-9302 is a competitive small molecule antagonist of transmembrane glutamine flux, that selectively and potently targets the amino acid transporter ASCT2(SLC1A5) with an IC50 value of 9.6 μM for inhibition of glutamine uptake in HEK-293 cells. V-9302 blocks Sodium-neutral AA transporter 2 (SNAT2, SLC38A2)and the large neutral AA transporter 1 (LAT1, SLC7A5)as observed in 143B osteosarcoma cells, HCC1806 breast cancer cells and Xenopus laevis oocytes. Dilution of PBS may cause a clear aqueous solution to turn into a uniform suspension.