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ZT-12-037-01
S-S8864-5mg
Producto nuevo
ZT-12-037-01
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Ficha de datos
| Size | 5mg |
| Target | Moleculas Pequeñas |
| CAS Number | 2328073-61-4 |
| Small Target | Serine/threonin kina |
| Pathway | Apoptosis |
| Smiles | COC1=CC2=NC(=NC(=C2C=C1OC)NC3CCN(CC3)C(C)C)NC4CC4 |
Más información
ZT-12-037-01 is a specific and ATP-competitive STK19inhibitor with IC50s of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N), respectively. It displays extremely high kinase selectivity using KINOMEscan against a panel of 468 diverse kinases using an in vitro ATP-site competition binding assay at 1 μM.