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Demethylnobiletin
S-S9421-1mg
Producto nuevo
2174-59-6
Al comprar este producto puede obtener hasta 15 puntos de fidelidad. Su cesta totalizará 15 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 3.00EUR.
Ficha de datos
| Size | 1mg |
| Target | Moleculas Pequeñas |
| CAS Number | 2174-59-6 |
| Small Target | Lipoxygenase |
| Pathway | Metabolism |
| Smiles | COC1=CC=C(C=C1OC)C2=CC(=O)C3=C(O2)C(=C(OC)C(=C3O)OC)OC |
Más información
Demethylnobiletin (5-Demethylnobiletin) is a unique flavonoid found in citrus fruits with potential chemopreventive effects against human cancers.5-Demethylnobiletin is a direct inhibitor of 5-LOX with IC50 of 0.1 μM, without affecting the expression of COX-2. 5-Demethylnobiletin has anti-inflammatory activity, inhibits leukotriene B 4(LTB4) formation in rat neutrophils and elastase release in human neutrophils with IC50 of 0.35 μM.