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Chemical Hay 28543 productos.
D-(+)-Trehalose dihydrate
D-(+)-Trehalose is a non-reducing sugar, used as a food ingredient and pharmaceutical excipient.
FHD-286
FHD-286 is a BRG1/BRM ATPase inhibitor, which can be used in the study of BAF-related diseases. Fdd-286 is also the first SMARCA2/SMARCA4 dual inhibitor. It can be used in the study of metastatic melanoma and advanced hematologic tumors.
LY2228820
LY2228820 is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM.
SAR-20347
SAR-20347 is a potent dual inhibitor of JAK1 and TYK2 with IC50 values of 23 and 0.6 nM, respectively.
Pevonedistat (MLN4924)
Pevonedistat (MLN4924) is a first-of-its-kind (first-in-class) small molecule inhibitor of Nedd8 activating enzyme (NAE) with an IC50 of 4.7 nM.
Stavudine
Stavudine (D4T) is a potent inhibitor of HIV-1 reverse transcriptase in vitro. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis.
Pralsetinib
Pralsetinib (BLU-667) is a next generation highly potent, selective RET inhibitor with IC50 of 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion.
Vinblastine sulfate
Vinblastine sulfate is an anti-mitotic agent which arrests the cell cycle in the G2/M-phase.
CK-636
CK-636 is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.
Diacerein
Diacerin is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.
Hyaluronidase (from sheep testes)
Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds. In addition, Hyaluronidase can be used to construct animal models of retinal detachment.
Luminespib (AUY922)
Luminespib (AUY922) is a small molecule Heat Shock Protein 90 (HSP90) inhibitor with IC50 values of 13 and 21 nM for HSP90α and HSP90β respectively.