Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
BAM7
BAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM.
LRRK2-IN-1
LRRK2-IN-1 is a potent and selective LRRK2 inhibitor with IC50 of 6 nM and 13 nM for LRRK2 (G2019S) and LRRK2 (WT), respectively.
Neobavaisoflavone
Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia.
SR17018
SR17018 is an mu-opioid-receptor (MOR) agonist, EC50 is 97 nM for binding with GTPγS.
Pirmenol hydrochloride
Pirmenol hydrochloride inhibits IK.ACh (IC50=0.1 μM) by blocking mAchR. Pirmenol hydrochloride can be used in the research of cardiovascular disease.
Ethosuximide
Ethosuximide is a succinimide anticonvulsant, used mainly in absence seizures; A calcium channel blocker.
TRV-120027 TFA
TRV-120027 (also known as TRV027) is an angiotensin II receptor type 1 (AT1R) antagonist and engages ß-arrestins while blocking G-protein signaling.
Ibezapolstat
Ibezapolstat (ACX-362E) is a first-of-its-kind (first-in-class) inhibitor of the orally active DNA polymerase IIIC (DNA pol IIIC) developed for use in the study of Clostridium difficile infection (CDI).
ABBV-744
ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of the BET family of proteins with IC50 values of 4-18 nM for BRD2, BRD3, BRD4, and BRDT for AML and metastatic desmoplasia-resistant prostate cancer.
CGP 60474
CGP60474 is a highly effective anti-endotoxin drug, It is an effective cyclin-dependent kinase (CDK) inhibitor (IC50 of CDK1/B, CDK2/E, CDK2/ A, CDK4/D, CDK5/ P25, CDK7/H and CDK9/T are 26, 3, 4, 216, 10, 200 and 13 nM, respectively). CGP60474 is a selective and ATP-competitive PKC inhibitor.
Sevelamer HCl
Sevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
Medetomidine hydrochloride
Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.