E3 ligase Ligand 2 (Thalidomide-4-OH) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein, it can be connected to the ligand for protein by a linker to form PROTACs.
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants.
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants.
Dorzagliatin (HMS-5552, RO-5305552, Sinogliatin) is a glucokinase (GK) activator, which improves glycaemic control and pancreatic β-cell function for type 2 diabetes.
Tetraethylammonium Chloride (TEACl) is a quaternary ammonium compound with the chemical formula C8H20N+Cl−, sometimes written as Et4N+Cl with a variety of applications.
PMX 205 Trifluoroacetate is a potent complement antagonist of C5a (C5aR; CD88) receptor.
PMX 205 Trifluoroacetate is a potent complement antagonist of C5a (C5aR; CD88) receptor.
PMX 205 Trifluoroacetate is a potent complement antagonist of C5a (C5aR; CD88) receptor.
GW627368X is a novel, potent and selective competitive antagonist of prostanoid EP4 receptors with additional human TP receptor affinity.
GW627368X is a novel, potent and selective competitive antagonist of prostanoid EP4 receptors with additional human TP receptor affinity.
Raphin1 is an orally bioavailable, selective R15B (PPP1R15B, a regulatory subunit of protein phosphatase 1) inhibitor, strongly binding to the R15B-PP1c holophosphatase with Kd of 33 nM.