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Raphin1 is an orally bioavailable, selective R15B (PPP1R15B, a regulatory subunit of protein phosphatase 1) inhibitor, strongly binding to the R15B-PP1c holophosphatase with Kd of 33 nM.
Carbutamide (BZ-55) is the first-generation orally active sulfonylurea with hypoglycemic activity.
Evocalcet is a calcium-sensitive receptor (CaSR) agonist that may be used in studies related to hypercalcemia and secondary hyperparathyroidism.
BI 882370 is a highly potent and selective RAF inhibitor that binds to the DFG-out (inactive) conformation of the BRAF kinase.
Evocalcet is a calcium-sensitive receptor (CaSR) agonist that may be used in studies related to hypercalcemia and secondary hyperparathyroidism.
Evocalcet is a calcium-sensitive receptor (CaSR) agonist that may be used in studies related to hypercalcemia and secondary hyperparathyroidism.
Histrelin is a nonapeptide analog of GnRH (gonadotropin-releasing hormone) with added potency.
Histrelin is a nonapeptide analog of GnRH (gonadotropin-releasing hormone) with added potency.
Rilzabrutinib, also known as PRN1008, is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK) with IC50 of 1.3 nM.
Rilzabrutinib, also known as PRN1008, is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK) with IC50 of 1.3 nM.
INE963 is an oral, single-dose, fast-acting blood-stage antimalarial candidate with an EC50 value of 3-6 nM.