Phytosphingosine is a phospholipid and has anti-cancer activities. Phytosphingosine induces cell apoptosis via caspase 8 activation and Bax translocation in cancer cells.
Zelasudil (RXC-007) is a selective ROCK2 inhibitor for studies related to idiopathic pulmonary fibrosis.
Zelasudil (RXC-007) is a selective ROCK2 inhibitor for studies related to idiopathic pulmonary fibrosis.
Gepirone (Gepirone) is a first-in-class, selective, affinity-based, orally active 5-HT1A receptor partial agonist as well as a 5-HT2A receptor antagonist for use in studies related to anxiety, depression, and chronic kidney disease.
Obicetrapib (DEZ-001) is a selective, orally active cholesterol transporter protein (CETP) inhibitor that blocks the function of CETP and significantly reduces LDL-C while significantly increasing HDL-C levels, and may be used in studies related to atherosclerosis and Alzheimer's disease (AD).
Gepirone (Gepirone) is a first-in-class, selective, affinity-based, orally active 5-HT1A receptor partial agonist as well as a 5-HT2A receptor antagonist for use in studies related to anxiety, depression, and chronic kidney disease.
Gepirone (Gepirone) is a first-in-class, selective, affinity-based, orally active 5-HT1A receptor partial agonist as well as a 5-HT2A receptor antagonist for use in studies related to anxiety, depression, and chronic kidney disease.
Dalbavancin hydrochloride is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria, and its MIC90 for inhibition of Staphylococcus aureus and Bacillus anthracis was 0.06 μg/mL and 0.25 μg/mL, respectively.
Dalbavancin hydrochloride is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria, and its MIC90 for inhibition of Staphylococcus aureus and Bacillus anthracis was 0.06 μg/mL and 0.25 μg/mL, respectively.
Fluvastatin is the first fully synthesized, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin protects vascular smooth muscle cells from oxidative stress through an Nrf2-dependent antioxidant pathway.
N-Butyl-N-(4-hydroxybutyl)nitrosamine can be used to construct animal models of bladder cancer (BLCA).
α-Conotoxin GI TFA is a short peptide toxin isolated from the venom of Conus geographus that has a high affinity for nAChR. α-Conotoxin GI TFA has similar activity to neuromuscular blocking agents.