Hirudin is a thrombin inhibitor with anticoagulant properties and strong antifibrotic and antitumor activity.
Acetyl tetrapeptide-2 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient.
Acetyl tetrapeptide-2 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient.
TC11 is a phenylphthalimide derivative and an activator of caspase-9 and CDK1, as well as a degrader of MCL1.TC11 is structurally related to immunomodulatory active molecules. During prolonged mitotic blockade, TC11 induces MCL1 degradation and leads to apoptotic death.
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm).
TC11 is a phenylphthalimide derivative and an activator of caspase-9 and CDK1, as well as a degrader of MCL1.TC11 is structurally related to immunomodulatory active molecules. During prolonged mitotic blockade, TC11 induces MCL1 degradation and leads to apoptotic death.
TC11 is a phenylphthalimide derivative and an activator of caspase-9 and CDK1, as well as a degrader of MCL1.TC11 is structurally related to immunomodulatory active molecules. During prolonged mitotic blockade, TC11 induces MCL1 degradation and leads to apoptotic death.
Sulfogaiacol is a antitussive agent. Sulfogaiacol is used for acute respiratory tract infections, cough and other conditions.
Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM.
Bis-PEG2-acid (COOH-PEG1-COOH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Bis-PEG2-acid (COOH-PEG1-COOH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PT-179 is an orthogonal Thalidomide (M2225) derivative that targets cereblon without causing off-target degradation effects. PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediate the degradation of the tagged protein.