Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
RSM-932A
RSM-932A (TCD-717) is a specific ChoKα inhibitor with IC50s of 1 and 33 μM for human recombinant ChoKα and ChoKβ enzymes, respectively. RSM-932A acts as the “first in humans” compound targeting ChoKα. RSM-932A is potent in vitro anti-proliferative and in vivo anti-tumoral activity against human xenografts in mice, showing high efficacy with low toxicity...
Lirafugratinib hydrochloride
Lirafugratinib hydrochloride is an orally active selective inhibitor of FGFR2.
Lirafugratinib hydrochloride
Lirafugratinib hydrochloride is an orally active selective inhibitor of FGFR2.
Cardanol monoene
Cardanol monoene (Cardanol C15:1) is a phenolic compound which can be found in cashew nut shell liquid. Cardanol monoene can induce mitochondria-associated apoptosis in human melanoma cells.
Kuguaglycoside C
Kuguaglycoside C is a triterpene glycoside that induces caspase‐independent DNA cleavage and cell death of neuroblastoma cells. Kuguaglycoside C also significantly increases the expression and cleavage of apoptosis-inducing factor (AIF).
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate is a cytomegalovirus CMV replication inhibitor, chelator, heavy metal detoxifier (e.g., acute cadmium toxicity), and radioactivity promoter, which improves solubility by forming water-soluble chelates with polyvalent cations.
Prussian blue
Prussian blue is an orally active compound that is also used as an antidote for poisoning by certain heavy metals, such as radioactive cesium or thallium ions, and as a contrast agent in magnetic resonance imaging (MRI). It also has anticancer and antibacterial properties. It can be used in contrast agent, antidote and cancer related research.
Ganoderma lucidum polysaccharide
Ganoderma lucidum polysaccharide, a major active ingredient in Ganoderma lucidum, inhibits hepatocellular carcinoma by regulating macrophage polarization and has immunomodulatory and antitumor activities.
Hydroethidine
Hydroethidine is a peroxide indicator that freely enters cells and dehydrogenates into ethidium bromide and distinguishes between superoxide and H2O2, and can be used to identify proliferating and hypoxic cells in tumors (λex=520 nm, λem=600 nm).
PK11007
PK11007 is a mild thiol alkylating agent with anticancer activity that stabilizes p53 through selective alkylation of two surface-exposed cysteines without affecting its DNA-binding activity. It also induces death of mutant p53 cancer cells by increasing reactive oxygen species (ROS) levels.
Ganoderma lucidum polysaccharide
Ganoderma lucidum polysaccharide, a major active ingredient in Ganoderma lucidum, inhibits hepatocellular carcinoma by regulating macrophage polarization and has immunomodulatory and antitumor activities.
