DNMDP, a phosphodiesterase 3A (PDE3A) inhibitor, is a potent and selective cancer cell cytotoxic agent. DNMDP binding to PDE3A promotes an interaction between PDE3A and Schlafen 12 (SLFN12). DNMDP shows clear cell-selective cytotoxicity.
TB500 is a synthetic version of an active region of thymosin β4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation.
TB500 is a synthetic version of an active region of thymosin β4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation.
Trifarotene (CD5789) is a potent and selective RARγ agonist. Trifarotene (CD5789) shows ∼65-fold and ∼16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM), respectively.
TB500 is a synthetic version of an active region of thymosin β4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation.
4,4'-Dimethoxychalcone acts as a natural autophagy inducer with anti-ageing properties.
4,4'-Dimethoxychalcone acts as a natural autophagy inducer with anti-ageing properties.
NF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM and induces superoxide dismutase (SOD)2 mRNA expression.
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate is a cytomegalovirus CMV replication inhibitor, chelator, heavy metal detoxifier (e.g., acute cadmium toxicity), and radioactivity promoter, which improves solubility by forming water-soluble chelates with polyvalent cations.
CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and possesses anti-leukemic activity.