trans Resveratrol 3-O-β-D-Glucuronide is a major metabolite of trans-resveratrol.
CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and possesses anti-leukemic activity.
CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and possesses anti-leukemic activity.
Hymeglusin is a β-lactone antibiotic with antifungal activity and an HMG-CoA synthase inhibitor with an IC50 value of 0.12 μM, which can inhibit HMG-CoA synthase by covalently modifying the active Cys129 residue of the enzyme.
Lifitegrast sodium is a potent integrin antagonist that blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen (LFA-1) and interrupts the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits the attachment of Jurkat T cells to ICAM-1 with an IC50 of 2.98 nM.May be useful in studies related to...
Fuzapladib is a leukocyte adhesion molecule and an orally active inhibitor of leukocyte function-associated antigen type 1 (LFA-1) activation.Fuzapladib is also a phospholipase A2 (PLA2) inhibitor, which exerts anti-inflammatory activity by inhibiting the migration of leukocytes to sites of inflammation.
GsMTx4 TFA is a spider venom peptide that selectively inhibits cation permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. In addition, GsMTx4 TFA blocks cation-selective stretch-activated channels (SACs) and attenuates lysophosphatidylcholine (LPC)-induced astrocytotoxicity and microglial cell reactivity.
α-Conotoxin AuIB TFA is a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist that blocks α3β4 nAChRs expressed in African clawed toad oocytes with an IC50 of 0.75 μM.
Nesiritide (Brain Natriuretic Peptide-32 human) is an agonist of natriuretic peptide receptors (NPRs), with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively.
Proteasome-activating peptide 1 is a peptide, which increases the chymotrypsin-like proteasomal catalytic activity and, consequently, proteolytic rates both in vitro and in culture.
Benproperine phosphate is an orally active, potent inhibitor of actin-associated protein 2/3 complex subunit 2 (ARPC2) that attenuates the rate of actin polymerization by impairing the function of Arp2/3.Benproperine phosphate inhibits cancer cell migration and tumor metastasis and has been used in studies related to cough. Benproperine phosphate inhibits...