BI-4020 is a fourth-generation, orally active, non-covalent EGFR tyrosine kinase macrocyclic inhibitors (TKIs). It inhibits the triple mutant EGFR del19 T790M C797S mutant (IC50=0.2 nM in the BaF3 cell line), the double mutant EGFR del19 T790M, and the single mutant EGFR del19 (IC50=1 nM). and also retains activity against EGFR wt (IC50=190 nM), which can...
RO27-3225 TFA is a potent, selective melanocortin type 4 receptor (MC4R) agonist with EC50s of 1 nM for MC4R and 8 nM for MC1R, with neuroprotective and anti-inflammatory activity, which attenuates gut dysfunction and brain damage.
Cholecystokinin (26-33), CCK8 TFA is a synthetic desulfated octapeptide cholecystokinin (CCK). Sequence: Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
RO27-3225 TFA is a potent, selective melanocortin type 4 receptor (MC4R) agonist with EC50s of 1 nM for MC4R and 8 nM for MC1R, with neuroprotective and anti-inflammatory activity, which attenuates gut dysfunction and brain damage.
RO27-3225 TFA is a potent, selective melanocortin type 4 receptor (MC4R) agonist with EC50s of 1 nM for MC4R and 8 nM for MC1R, with neuroprotective and anti-inflammatory activity, which attenuates gut dysfunction and brain damage.
C-Peptide TFA is a component of insulinogen, which is released into the bloodstream from pancreatic islet B cells along with insulin.
C-Peptide TFA is a component of insulinogen, which is released into the bloodstream from pancreatic islet B cells along with insulin.
MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM) and a partial agonist at human MC3 and MC5 receptors (EC50 values of 59 and 1300 nM, respectively). In addition, MSG606 TFA reversed the hyperalgesia induced in female mice but had no effect in male mice.
RNase Inhibitor, Murine specifically inhibits RNases A, B and C, thereby protecting RNA from degradation by these enzymes.
Gp100 (25-33), mouse sequence is found in residues 25 to 33 of the mouse self/tumor antigen glycoprotein (mgp100).