VCAM-1 is a single-pass type I membrane protein, and mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate.
B-cell leukemia/lymphoma 2, also known as Bcl-2, belongs to the Bcl-2 family. BCL2 blocks the apoptotic death of some cells such as lymphocytes. It also regulates cell death by controlling the mitochondrial membrane permeability and inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the...
KGF/Fibroblast growth factor 7 (FGF7) plays an important role in regulating the proliferation, migration, and differentiation of cells. FGF7 is of stromal origin and produces a paracrine effect on epithelial cells.
Recombinant human t cell specific surface glycoprotein CD28 is produced by mammalian expression systems, and the target gene encoding Asn19-Pro152 is expressed in the N-terminal with the 6His tag. Protein number: P10747.
Interleukin-2 (IL-2) is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric...
GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells.
Recombinant mouse fibroblast growth factor 4 was produced by escherichia coli expression system and expressed the target gene encoding Ser67 -- Leu202. Accession # : P11403.
Macrophage inflammatory protein 1β (MIP-1β), also known as Chemokine (C-motif) ligand 4 (CCL4), is a small cytokine in the CC Chemokine family. It is a chemical attractant for natural killer cells, monocytes and a variety of other immune cells. Protein structure: MIP-1β (ALA24-ASN92), Accession # P13236-1.
Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
Adiponectin is a hormone mainly produced by adipocytes. Adiponectin forms a homotrimer and exists as higher order multimers in vivo. Measured by a cell growth inhibitory assay using M1 cells, the ED50 is < 5.0 µg/ml, corresponding to a specific activity of > 2.0 × 102 units/mg.
FLT3-ligand (HEK293) is a growth factor that regulates the proliferation of early hematopoietic cells. FLT 3-ligand binds to cells expressing FLT 3, the tyrosine kinase receptor.