Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherin-17 plays a role in the morphological organization of liver and intestine and involved in intestinal peptide transport.
Ravulizumab (ALXN1210) is a humanized monoclonal antibody that binds with high affinity to complement protein C5 and inhibits terminal complement activation, Ravulizumab can be used for the researchs of COVID-19-associated severe pneumonia, acute lung injury and acute respiratory distress syndrome.
TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. TFAP2C may be prognostic indicators for breast tumors.
Recombinant mouse interleukin-15 receptor subunit α is produced by mammalian expression systems, and the target gene encoding Gly33-Lys205 is expressed with Fc tag at the C-terminal. Protein number: Q60819.
Nivolumab (nabumab) is a fully humanized IgG4 monoclonal antibody against PD-1. It has immune checkpoint inhibitory activity and antitumor activity; MW: 143.597 KD.(for human-derived mice).
Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream.
Nimotuzumab (Nimotuzumab) is the first humanized monoclonal antibody targeting epidermal growth factor receptor (EGFR). Nimotuzumab has cytolytic effects on target tumors through its ability to induce antibody-dependent cell-mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC). Nimotuzumab failed to recognize mouse EGFR.
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes, and found in liver, fetal liver, bone marrow, placenta, spleen and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2,3- or alpha-2,6-linked sialic acid.
COX-2 is s component of Prostaglandin-endoperoxide synthase (PTGS). It is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase.
Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases.
The recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression systems, and the target gene encoding Asp23-Asp126 is expressed by 6His tag at the C-terminal. Protein number: P07766.
Recombinant Mouse IL-13 Protein is an immunoregulatory cytokine belonging to the IL-4/IL-13 family, a multifunctional cytokine whose main role is to reduce the inflammatory response.