Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses. Measured in a bioassay using 7TD1 cells, the ED50 is < 3.0 pg/ml.
Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into...
Interleukin-10 (IL-10) is produced by many immune cells, such as T-cells, macrophages, mast cells and dendritic cells. It is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and Th2 cells.
Human IFN-α2a and -α2b (HEK293) are allelic variants of the same gene, the IFN-α subtype is classified as an intermediate/strong ISG inducer and has strong antiviral activity against influenza A virus.
ED50 < 4.0 pg/ml, measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D, corresponding to a specific activity of > 2.5 × 108 units/mg.
Recombinant Human MMP-2 (also known as matrix metalloproteinase-2) is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. MMP-2 can act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. The proenzyme needs to be activated by APMA for an activated...
Nirsevimab (MEDI8897) is a recombinant human respiratory syncytial virus (RSV) monoclonal antibody with modified Fc region, which can prolong its half-life. Nirsevimab has an affinity for RSV-B with an Kd value of 1.5 nM. Nirsevimab can be used for RSV research.
Recombinant Rat IL-4 Protein is a multidirectional cytokine that regulates various T cell and B cell responses such as cell proliferation, survival, and gene expression.
Vunakizumab (Anti-Human IL17A Recombinant Antibody) is a recombinant human IgGκ monoclonal antibody that targets IL-17A and inhibits its interaction with the IL-17 receptor. Vunakizumab can be used to study autoimmune diseases such as psoriatic arthritis, ankylosing spondylitis, multiple sclerosis and inflammatory arthritis.
Recombinant mouse/rat transforming growth factor β1 is produced by the mammalian expression system and the target gene encoding Ala279-Ser390 is expressed. Measured by its ability to inhibit IL-4-dependent proliferation of TF‑1 human erythroleukemic cells.The ED50 for this effect is 5-25 pg/ml.
Recombinant Human CD19 Protein (HEK293) Protein sequence: THE DNA sequence encoding human CD19 (UniProtKB/ Swiss-PROt: P15391.6) was expressed with His tag at the C-terminal. Bioactivity: Immobilized CD19 monoclonal antibody at 5μg/mL (100 μL/ well) can bind CD19 protein in a linear range of 5-100ng/mL
Basic fibroblast growth factor (FGF-BASIC), also known as HBGF-2, is a non-glycosylated heparin binding growth factor that belongs to the FGF family. Expressed with an N-terminal Met. Pro10-ser154), Accession # P15655.