Platelet factor 4 (PF-4/CXCL4) is expressed in megakaryocytes and stored in the α-granules of platelets. Recombinant human PF-4 can be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation. Recombinant Mouse Prolactin/PRL Protein is produced by Mammalian expression system and the target gene encoding Leu32-Cys228 is expressed with a 6His tag at the C-terminus.
Recombinant human CNTF protein (HEK 293) was isolated and purified from chick embryo eye tissue. It was identified as a nutrient factor of chick embryo parasympathetic nerve cells by culture. Protein structure: CNTF (MET1-MET200), Accession # P26441-1.
Stromal cell-derived factor-1 α / CXCL12 (SDF-1α) and SDF-1β, members of the α subfamily of chemokines lacking the ELR domain, were originally identified from mouse bone marrow stromal cell lines using a signal-sequence trap cloning strategy. Protein construction: SDF-1α/CXCL12 (Lys22-LYS89), Accession # : Q4FJL5.
Recombinant human interferon Alpha-2a was produced by an E. coli expression system. Protein No. P01563. ED50 < 0.1 ng/ml, measured by cytotoxicity assay using TF-1 cells, corresponding to specific activity > 1.0 × 107 units/mg.
Tissue-type plasminogen activator (TPA) is a protein that secreted into extracellular space. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, TPA plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and...
Interleukin 1 beta (IL-1β) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells.
Lactoferrin (LTF) is a major iron-binding protein in exocrine fluid and controls the level of free iron in the blood and external secretions. It exhibits multiple antibacterial effects by chelating iron and disrupting bacterial membranes.
Fibroblast Growth Factor 9 (FGF-9) is a hormone-regulated survival Factor of mitogen and nerve mesenchymal cells.
Osteopontin/SPP1 is a secreted multifunctional glycoprotein. Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression. Osteopontin/SPP1 acts as a cytokine that is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10.
Ravulizumab (ALXN1210) is a humanized monoclonal antibody that binds with high affinity to complement protein C5 and inhibits terminal complement activation, Ravulizumab can be used for the researchs of COVID-19-associated severe pneumonia, acute lung injury and acute respiratory distress syndrome.
POSTN (Periostin, OSF-2) is a secreted, homodimeric protein that belongs to the periostin family of the FAS1 superfamily of molecules. It is a TGF-beta inducible molecule that serves as both an adhesion molecule and tumor suppressor.