Elotuzumab is a First-in-Class monoclonal antibody directed against the SLAMF7 receptor, it specifically binds to signaling lymphocyte activating molecule family member 7 (SLAMF7) and activates the body's immune response to attack and kill multiple myeloma cells. Elotuzumab exerts its anti-myeloma effects mainly through ADCC and activation of NK cells.
Recombinant ASFV p72 complex is produced by Mammalian expression system and the target gene encoding Met1-Thr646&Met1-Leu530 is expressed with a 10His-3*Flag tag and a Flag-Strep tag at the N-terminus. Protein p72 is the major capsid protein of African swine fever virus (ASFV) and is an important target for test and vaccine development.
R-spondin-3 (RSPO3) is a member of the thrombospondin type 1 repeat supergene family. RSPO3 founctions as a activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation.
GAS6 (Growth arrest-specific protein 6) also known as AXL receptor tyrosine kinase ligand, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest.
Cathepsin B is an enzymatic protein that is a member of the peptidase (or protease) family.
Recombinant Murine GM-CSF Protein is a hematopoietic growth factor that can promote the development of neutrophils and macrophages, and promote the proliferation and development of early erythroid megakaryocytes and eosinophilic progenitors.
Chemokine (C-C Motif) Ligand 7 (CCL7) is a small cytokine formerly known as monocyte specific chemokine 3 (McP-3). Protein structure: MCP 3 (GLN34-LEU109),Accession # : Q7Z7Q8.
Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Human serum albumin is a protein found in human plasma. Its non-glycosylated, single-chain polypeptide contains 585 amino acids, has a molecular weight of 66 kD, transports fatty acids, bile pigments, amino acids, and steroid hormones, and serves as an excipient, stabilizer, and encapsulant.
Fibroblast Growth Factor-9 (FGF-9) is a heparin binding growth factor that belongs to the fibroblast growth factor (FGF) family. ED50 < 2.0 ng/ mL, determined by 3T3 cell proliferation assay, corresponding to > 5.0× 105 units/mg.
Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung.
FGF acid, also known as ECGF, FGF-1 and HBGF-1, is a non-glycosylated heparin-binding growth factor expressed in brain, kidney, retina, smooth muscle cells, bone stroma, osteoblasts, astrocytes and endothelial cells.