Mouse MFGE8 Protein contributes to phagocytic removal of apoptotic cells in many tissues. It plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing.
Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 stimulates the development and colony formation of multiple lineages of hematopoietic cells by activating intracellular pathways such as Ras-Raf-ERK and JAK/STAT. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family.
Interleukin-10 (IL-10) is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and Th2 cells.
Pd-1 (Programmed Cell death protein 1), also known as PDCD1, is an important immunosuppressive transmembrane protein expressed on the surface of T cells. The protein Sequence of this product is the expression of DNA Sequence encoding human PD-1 (NCBI Reference Sequence: NP_005009.2) with Fc label at the C-terminal.
Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.
Vonlerolizumab (MOXR 0916) is a humanized IgG agonistic monoclonal OX40-specific antibody. Vonlerolizumab can be used for the research of cancer.
Recombinant Human IGF-1 LR3 Protein is a mitogenic polypeptide growth factor that can stimulate the proliferation and survival of various cells, including muscle, bone and cartilage tissue.
Human M-CSF protein (CHO) is a hematopoietic growth factor with multiple glycoylation sites, which can affect the survival and function of macrophages and has antitumor activity. It was expressed by CHO cells.
GDC-0853 (Fenebrutinib) is a potent, selective and non-covalent bruton tyrosine kinase (Btk) inhibitor with a Ki value of 0.91 nM against BRK.
Recombinant human Mammalian timP-2 protein (C-6HIS) is produced by the Mammalian expression system, and the target gene encoding CYS27-PRO220 expresses the 6His marker at the C-terminal. Accession # : P16035.
Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research.