Recombinant rat tumor necrosis factor produced in Pichia pastoris. TNF-alpha plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune disease. ED50 < 50.0 pg/ml
Recombinant Human IGF-1 LR3 Protein is a mitogenic polypeptide growth factor that can stimulate the proliferation and survival of various cells, including muscle, bone and cartilage tissue.
Recombinant Human IL-15 Protein is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor.
Macrophage inflammatory protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine in the CC chemokine family. Accession P97884 - # 1.
IL-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R). Measured in a cell proliferation assay using human peripheral blood mononuclear cell, the ED50 is 2-8 ng/mL.
Recombinant Mouse IGF-I belongs to the IGF family of peptides, which also includes IGF-II and insulin. IGF-I executes its functions via signaling through transmembrane tyrosine receptors (IGF Receptors). ED50 < 10.0 ng/ml, measured by a cell proliferation assay using FDC-P1 cells, corresponding to a specific activity of > 1.0 × 105 units/mg.
Dickkopf related protein 1 (DKK-1) is a chemokine that belongs to the DKK protein family, promotes LRP6 internalization and degradation as it forms a ternary complex with the cell surface receptor Kremen. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. ED50 < 6.0 µg/ml, measured in...
Macrophage inflammatory protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine in the CC chemokine family. Accession P97884 - # 1.
Recombinant Human IL-15 Protein is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor.
Recombinant Mouse RANK (Receptor Activator of NF-kappa B) is produced by Mammalian expression system and the target gene encoding Val31-Ser214 is expressed with a 6His tag at the C-terminus. RANK can activate signaling pathways such as NF-κB, JNK, ERK, p38, and Akt/PKB, through TRAF protein phosphorylation after binding its ligand RANKL.
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes. Recombinant Human Matrix Metalloproteinase-3 is produced by Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus.The proenzyme...
Recombinant Human IL-18 (also known as γ-interferon-inducible factor) is an inflammatory cytokine belonging to the interleukin-1 family and can be produced by macrophages and other cells.