Dickkopf related protein 1 (DKK-1) is a chemokine that belongs to the DKK protein family, promotes LRP6 internalization and degradation as it forms a ternary complex with the cell surface receptor Kremen. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. ED50 < 6.0 µg/ml, measured in...
Recombinant Human Vimentin Protein is a type III intermediate filament protein, which mainly exists in cells of mesenchymal origin, such as vascular endothelial cells and blood cells, and is the main component of the cytoskeleton.
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes. Recombinant Human Matrix Metalloproteinase-3 is produced by Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus.The proenzyme...
Recombinant mouse hepatitis A virus cell receptor 1 homolog is produced by a mammalian expression system and the target gene encoding Tyr22Thr212 has a 6His tag at the C-terminus. Protein number: Q5QNS5.
Human Interleukin-33 (IL-33) is a proinflammatory cytokine that belongs to the IL-1 family. IL-33 plays a role in autoimmune disease. IL-33’s interaction with ST2 can drive allergic pathology and IL-33 has been reported to play a role in the development of rheumatoid arthritis and systemic lupus erythematosus.
Recombinant human Heregulin β-1 protein is a member of the EGF family of proteins. Heregulin is essential for the normal development of the nervous system and the heart. It is produced in numerous isoforms by alternative splicing, allowing it to perform a variety of functions.
Recombinant Mouse IGF-I belongs to the IGF family of peptides, which also includes IGF-II and insulin. IGF-I executes its functions via signaling through transmembrane tyrosine receptors (IGF Receptors). ED50 < 10.0 ng/ml, measured by a cell proliferation assay using FDC-P1 cells, corresponding to a specific activity of > 1.0 × 105 units/mg.
Recombinant human Heregulin β-1 protein is a member of the EGF family of proteins. Heregulin is essential for the normal development of the nervous system and the heart. It is produced in numerous isoforms by alternative splicing, allowing it to perform a variety of functions.
Recombinant Human IFN-λ1 Protein uses an independent receptor system consisting of IFN-λR1 subunit (also called CRF 2-12) and IL-10R2 subunit (also called CRF 2-14) to induce an antiviral defense similar to type I interferon, but different from type I interferon.
Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP-1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens. The target gene encoding Phe20-Asn469 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA...