CPI-1205 is a highly potent (biochemical IC50 = 0.002 μM, cellular EC50 = 0.032 μM) and selective inhibitor of EZH2.
Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) is a homobifunctional, cleavable cross-linking reagent, it is mainly coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).
(R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase.
Amylin, amide, human is a 37-amino acid polypeptide, it is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis.
Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH TFA is a substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2).
Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH TFA is a substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2).
dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC) which exhibits significant and selective degradation of BRD4 BD1 but is inactive on BRD4 BD2.