Exenatide Acetate (Exendin-4) is a first-in-class glucagon-like peptide 1 (GLP-1) receptor agonist consisting of 39 amino acids.
SY-5609 (CDK7-IN-3) is an orally active, highly selective, noncovalent CDK7 inhibitor with a KD of 0.065 nM. SY-5609 shows poor inhibition on CDK2 (Ki=2600 nM), CDK9 (Ki=960 nM), CDK12 (Ki=870 nM).
TPX-0046 is a novel RET/SRC inhibitor that is used against RET in Ba/F3 cell proliferation assaysG810R The average IC50 is 17 nM.
Coenzyme Q9 (Ubiquinone Q9), the main form of rodent ubiquinone, is a biparent molecular component in the electron transport chain that acts as an endogenous antioxidant. Coenzyme Q9 mitigates a decline in antioxidant defense mechanisms caused by diabetes. Coenzyme Q9 improves left ventricular function, reduces myocardial infarction area and apoptosis of...
SY-5609 (CDK7-IN-3) is an orally active, highly selective, noncovalent CDK7 inhibitor with a KD of 0.065 nM. SY-5609 shows poor inhibition on CDK2 (Ki=2600 nM), CDK9 (Ki=960 nM), CDK12 (Ki=870 nM).
RCGD423 is a gp130 regulator that prevents joint cartilage degeneration and promotes its repair.
RCGD423 is a gp130 regulator that prevents joint cartilage degeneration and promotes its repair.
(Z)-Aconitic acid (cis-Aconitic acid) is a cis isomer of Aconitic acid. (Z)-Aconitic acid (cis-Aconitic acid) is an intermediate product of the isomerization of citrate into isocicirate in the tricarboxylic acid cycle.
Methyl α-D-glucopyranoside can be used in a study to investigate saccharide-mediated protection of chaotropic-induced deactivation of concanavalin A.
UC2288 is a novel p21 attenuator with cellular permeability and oral activity (relatively selective activity for P21), based on the structural synthesis of sorafenib. UC2288 down-regulated the expression of P21 mRNA and reduced the level of P21 protein independently of p53, and had little effect on the stability of P21 protein. UC2288 did not inhibit...
UC2288 is a novel p21 attenuator with cellular permeability and oral activity (relatively selective activity for P21), based on the structural synthesis of sorafenib. UC2288 down-regulated the expression of P21 mRNA and reduced the level of P21 protein independently of p53, and had little effect on the stability of P21 protein. UC2288 did not inhibit...
Autotaxin Modulator 1 is an Autotaxin (ATX) inhibitor of Autotaxin (ATX). Autotaxin Modulator 1 is expected to be used for demyelination caused by injury or disease, as well as for the study of proliferative diseases such as tumors.